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Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. Any process that stops, prevents, or reduces the rate of production of a cytokine. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that modulates the frequency, rate, or extent of production of a cytokine. Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production. Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of type I interferon production
Acc: GO:0032480
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:
  • down-regulation of type I interferon production
  • inhibition of type I interferon production
  • negative regulation of type I IFN production
  • down regulation of type I interferon production
  • downregulation of type I interferon production
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032480 - negative regulation of type I interferon production (interactive image map)

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