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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process. Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA. The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences. Any process that stops, prevents or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA. Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. Any process that stops, prevents or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The process whereby telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors. Any process that modulates the frequency, rate or extent of DNA replication.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of telomere maintenance via semi-conservative replication
Acc: GO:0032214
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
Synonyms:
  • inhibition of telomere maintenance via semi-conservative replication
  • down-regulation of telomere maintenance via semi-conservative replication
  • down regulation of telomere maintenance via semi-conservative replication
  • downregulation of telomere maintenance via semi-conservative replication
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032214 - negative regulation of telomere maintenance via semi-conservative replication (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle