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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. That part of the nuclear content other than the chromosomes or the nucleolus. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: integrator complex
Acc: GO:0032039
Aspect: Cellular Component
Desc: A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032039 - integrator complex (interactive image map)

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