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The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of glucocorticoid biosynthetic process
Acc: GO:0031947
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
Synonyms:
  • down regulation of glucocorticoid biosynthetic process
  • downregulation of glucocorticoid biosynthetic process
  • inhibition of glucocorticoid biosynthetic process
  • down-regulation of glucocorticoid biosynthetic process
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031947 - negative regulation of glucocorticoid biosynthetic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle