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The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate or extent of B cell activation. The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. Any process that activates or increases the frequency, rate or extent of lymphocyte activation. The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation. Any process that activates or increases the frequency, rate or extent of B cell activation. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: B cell costimulation
Acc: GO:0031296
Aspect: Biological Process
Desc: The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.
Synonyms:
  • B lymphocyte co-stimulation
  • B-cell co-stimulation
  • B-cell costimulation
  • B-lymphocyte co-stimulation
  • B cell co-stimulation
  • B-lymphocyte costimulation
  • B lymphocyte costimulation
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031296 - B cell costimulation (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle