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Any process that modulates the frequency, rate or extent of the process of creating protein polymers. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization. The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. The addition of tubulin heterodimers to one or both ends of a microtubule. Any process that stops, prevents or reduces the frequency, rate or extent of protein complex assembly. Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. Any process that stops, prevents or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. Any process that stops, prevents or reduces the frequency, rate or extent of the process of creating protein polymers. Any process that modulates the frequency, rate or extent of microtubule polymerization. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of microtubule polymerization
Acc: GO:0031115
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization.
Synonyms:
  • down-regulation of microtubule polymerization
  • down regulation of microtubule polymerization
  • downregulation of microtubule polymerization
  • inhibition of microtubule polymerization
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031115 - negative regulation of microtubule polymerization (interactive image map)
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