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A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). The lipid bilayer surrounding the platelet alpha granule. A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. The lipid bilayer surrounding a cytoplasmic vesicle. The lipid bilayer surrounding a secretory granule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: platelet alpha granule membrane
Acc: GO:0031092
Aspect: Cellular Component
Desc: The lipid bilayer surrounding the platelet alpha granule.
Synonyms:
  • platelet alpha-granule membrane
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031092 - platelet alpha granule membrane (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle