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Any process that modulates the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region. Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. The process by which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA. Any epigenetic process that stops, prevents or reduces the rate of gene expression. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. The process by which an siRNA-associated RNA-induced silencing complex (siRISC) associates with nascent transcripts and RNA polymerase to induce the formation of heterochromatin. Any process by which RNA molecules inactivate expression of target genes. Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription. Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA. Any process that decreases the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chromatin silencing by small RNA
Acc: GO:0031048
Aspect: Biological Process
Desc: Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.
Synonyms:
  • RNA interference-like chromatin silencing
  • RNA-mediated transcriptional silencing
  • small RNA-mediated heterochromatic silencing
  • RNAi-like chromatin silencing
  • RNA-mediated chromatin silencing
  • RNA-mediated TGS
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 23 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031048 - chromatin silencing by small RNA (interactive image map)
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