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The proteolytic degradation of proteins in the cytosol that contributes to apoptosis. A cellular process that results in the breakdown of a part of the cell. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cleavage of cytosolic proteins involved in apoptosis
Acc: GO:0030972
Aspect: Biological Process
Desc: The proteolytic degradation of proteins in the cytosol that contributes to apoptosis.
Synonyms:
  • apoptotic cleavage of cytosolic proteins
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030972 - cleavage of cytosolic proteins involved in apoptosis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle