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Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain. The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases. Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament. Any process that modulates the frequency, rate or extent of the process of creating protein polymers. Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that activates or increases the frequency, rate or extent of protein complex assembly. Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament. Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of intermediate filament polymerization
Acc: GO:0030841
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.
Synonyms:
  • up regulation of intermediate filament polymerization
  • activation of intermediate filament polymerization
  • up-regulation of intermediate filament polymerization
  • positive regulation of intermediate filament polymerization and/or depolymerization
  • stimulation of intermediate filament polymerization
  • upregulation of intermediate filament polymerization
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030841 - positive regulation of intermediate filament polymerization (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle