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Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: CMP-N-acetylneuraminate monooxygenase activity
Acc: GO:0030338
Aspect: Molecular Function
Desc: Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.
Synonyms:
  • CMP-N-acetylneuraminic acid hydroxylase activity
  • CMP-Neu5Ac hydroxylase activity
  • cytidine monophosphoacetylneuraminate monooxygenase activity
  • CMP-N-acetylneuraminate hydroxylase activity
  • CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)
  • cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity
  • N-acetylneuraminic monooxygenase activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030338 - CMP-N-acetylneuraminate monooxygenase activity (interactive image map)
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Created and Maintained by: Michael Riffle