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Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. Any process that modulates the frequency, rate or extent of a response to an external stimulus. The process by which a fluid solution, or part of it, changes into a solid or semisolid mass. The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. Any process that stops, prevents or reduces the frequency, rate or extent of coagulation. Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass. Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that modulates the frequency, rate or extent of blood coagulation. The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation. The series of events that restore integrity to a damaged tissue, following an injury. An ongoing process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, resulting in the removal of small blood clots.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of blood coagulation
Acc: GO:0030195
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation.
Synonyms:
  • downregulation of blood coagulation
  • down-regulation of blood coagulation
  • down regulation of blood coagulation
  • inhibition of blood coagulation
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 42 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030195 - negative regulation of blood coagulation (interactive image map)
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