YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. The generation of a mature peptide hormone by posttranslational processing of a prohormone. The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: insulin processing
Acc: GO:0030070
Aspect: Biological Process
Desc: The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030070 - insulin processing (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle