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The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The differentiation of cells that will contribute to the structure and function of the hypothalamus. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone. The process whereby a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hypothalamus gonadotrophin-releasing hormone neuron fate commitment
Acc: GO:0021887
Aspect: Biological Process
Desc: The process whereby the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0021887 - hypothalamus gonadotrophin-releasing hormone neuron fate commitment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle