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Process whereby serine carried by a specialized tRNA(ser) (which can read a UGA anticodon) is converted to selenocysteine. Process whereby lysine carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon) is converted to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate). The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. Process whereby glutamate charged on a tRNA(Gln) is converted to glutaminyl-tRNA. The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. Process whereby aspartate charged on a tRNA(Asn) is converted to asparaginyl-tRNA. The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: charged-tRNA amino acid modification
Acc: GO:0019988
Aspect: Biological Process
Desc: The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.
Synonyms:
  • charged-tRNA modification
  • pre-translational amino acid modification
  • pretranslation protein modification
  • pretranslational amino acid modification
  • pre-translational protein modification
  • GO:0030630
  • charged tRNA amino acid modification
  • charged tRNA modification
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019988 - charged-tRNA amino acid modification (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle