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Catalysis of the reaction: indole-3-acetonitrile (IAN) + H2O = indole-3-acetamide (IAM). Catalysis of the breakage of a carbon-oxygen bond. Catalysis of the reaction: an aliphatic amide = a nitrile + H2O. Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: nitrile hydratase activity
Acc: GO:0018822
Aspect: Molecular Function
Desc: Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.
Synonyms:
  • acrylonitrile hydratase activity
  • 3-cyanopyridine hydratase activity
  • aliphatic-amide hydro-lyase (nitrile-forming)
  • NHase activity
  • L-NHase activity
  • nitrile hydro-lyase activity
  • aliphatic nitrile hydratase activity
  • H-NHase activity
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0018822 - nitrile hydratase activity (interactive image map)
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Created and Maintained by: Michael Riffle