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Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R. Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
Acc: GO:0017060
Aspect: Molecular Function
Desc: Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
Synonyms:
  • blood group Lewis alpha-4-fucosyltransferase activity
  • Lewis alpha-(1->3/4)-fucosyltransferase activity
  • blood group Lewis alpha-4-fucosyltransferase
  • Lewis blood group alpha-(1->3/4)-fucosyltransferase activity
  • blood-group substance Lea-dependent fucosyltransferase
  • GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity
  • alpha-(1->4)-L-fucosyltransferase activity
  • Lewis FT activity
  • blood-group substance Le(a)-dependent fucosyltransferase activity
  • alpha-4-L-fucosyltransferase activity
  • guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity
  • beta-acetylglucosaminylsaccharide fucosyltransferase activity
  • Lewis alpha-(1->3/4)-fucosyltransferase
  • (Le(a))-dependent (alpha-3/4)-fucosyltransferase activity
  • (Lea)-dependent (alpha-3/4)-fucosyltransferase activity
  • alpha(1,4)-L-fucosyltransferase activity
  • GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity
  • FucT-II activity
  • alpha(1,3/1,4) fucosyltransferase III
  • galactoside 3(4)-L-fucosyltransferase activity
  • 3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
  • guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity
  • Lewis blood group alpha-(1->3/4)-fucosyltransferase
  • Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase
  • guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity
  • alpha-(1,3/1,4) fucosyltransferase III activity
  • Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017060 - 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity (interactive image map)

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