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null Catalysis of the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors. null Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines. Catalysis of the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: SAP kinase activity
Acc: GO:0016909
Aspect: Molecular Function
Desc: Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.
Synonyms:
  • stress-activated kinase activity
  • stress-activated protein kinase activity
  • SAPK
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016909 - SAP kinase activity (interactive image map)
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Created and Maintained by: Michael Riffle