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Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. Any process that modulates the frequency, rate or extent of muscle hypertrophy. Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of muscle hypertrophy
Acc: GO:0014743
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of muscle hypertrophy.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014743 - regulation of muscle hypertrophy (interactive image map)
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