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A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of neuron maturation. Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that modulates the frequency, rate or extent of neuron differentiation. A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of neuron maturation
Acc: GO:0014043
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of neuron maturation.
Synonyms:
  • inhibition of neuron maturation
  • down regulation of neuron maturation
  • down-regulation of neuron maturation
  • downregulation of neuron maturation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014043 - negative regulation of neuron maturation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle