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The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast. The process whereby a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Generation of cells within the nervous system.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: neuroblast differentiation
Acc: GO:0014016
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 46 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014016 - neuroblast differentiation (interactive image map)
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