YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. Any process that modulates the frequency, rate or extent of muscle adaptation. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that modulates the frequency, rate or extent of muscle hypertrophy. Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of cardiac muscle hypertrophy
Acc: GO:0010614
Aspect: Biological Process
Desc: Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010614 - negative regulation of cardiac muscle hypertrophy (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle