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Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-hydroxybutyryl-CoA dehydrogenase activity
Acc: GO:0008691
Aspect: Molecular Function
Desc: Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.
Synonyms:
  • L(+)-3-hydroxybutyryl-CoA dehydrogenase activity
  • beta-hydroxybutyryl-CoA dehydrogenase activity
  • BHBD activity
  • (S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity
  • dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)
  • beta-hydroxybutyryl coenzyme A dehydrogenase activity
  • L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008691 - 3-hydroxybutyryl-CoA dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle