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Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to an oligosaccharide. Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
Acc: GO:0008454
Aspect: Molecular Function
Desc: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.
Synonyms:
  • UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity
  • beta-acetylglucosaminyltransferase IV activity
  • GnTIV activity
  • alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity
  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity
  • uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity
  • uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV
  • alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity
  • N-acetylglucosaminyltransferase IV activity
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008454 - alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (interactive image map)
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