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Any process that activates or increases the frequency, rate or extent of the DNA-dependent transcription of a specific gene or genes. Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating endoplasmic reticulum (ER) stress. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). Any process that modulates the DNA-dependent transcription of a specific gene or genes. The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response. Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter. Any process that activates or increases the frequency, rate or extent of cellular DNA-dependent transcription. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of gene-specific transcription involved in unfolded protein response
Acc: GO:0006990
Aspect: Biological Process
Desc: The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.
Synonyms:
  • unfolded protein response, stimulation of target gene transcription
  • unfolded protein response, target gene transcriptional activation
  • unfolded protein response, positive regulation of target gene transcription
  • unfolded protein response, up regulation of target gene transcription
  • unfolded protein response, activation of target gene transcription
  • positive regulation of transcription of target genes involved in unfolded protein response
  • unfolded protein response, upregulation of target gene transcription
  • unfolded protein response, up-regulation of target gene transcription
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006990 - positive regulation of gene-specific transcription involved in unfolded protein response (interactive image map)
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Created and Maintained by: Michael Riffle