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The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions. The orderly movement of a cell from one site to another, often during the development of a multicellular organism or multicellular structure. The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate. The attachment of a cell to the underlying substrate via adhesion molecules. The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: substrate-bound cell migration, cell attachment to substrate
Acc: GO:0006931
Aspect: Biological Process
Desc: The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006931 - substrate-bound cell migration, cell attachment to substrate (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle