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Any process that protect an organism from invading foreign DNA by methylation of self DNA at specific sequences and nucleolytic cleavage of unmethylated foreign DNA. Any cellular metabolic process involving nucleic acids. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. The covalent attachment of an ADP-ribosyl moiety to the amino group at N2 of a 2'-deoxyguanosine residue in double-stranded DNA. The removal of an alkyl group from one or more nucleotides within an DNA molecule. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil. The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar. The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar. The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA modification
Acc: GO:0006304
Aspect: Biological Process
Desc: The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 193 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006304 - DNA modification (interactive image map)
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