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A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes. Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome. A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: secondary lysosome
Acc: GO:0005767
Aspect: Cellular Component
Desc: Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 17 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005767 - secondary lysosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle