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Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Combining with a cytokine to initiate a change in cell activity. Combining with a C-X-C chemokine to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. Combining with chemokines, small chemoattractant molecules normally used to stimulate leukocytes, to initiate a change in cell activity. Combining with interleukin-8 to initiate a change in cell activity. Interacting selectively and non-covalently with interleukin-8. Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif. Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: interleukin-8 receptor activity
Acc: GO:0004918
Aspect: Molecular Function
Desc: Combining with interleukin-8 to initiate a change in cell activity.
Synonyms:
  • IL-8R
  • IL-8 receptor activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004918 - interleukin-8 receptor activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle