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Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Acc: GO:0004639
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate.
Synonyms:
  • PurC
  • 4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity
  • 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity
  • phosphoribosylaminoimidazole-succinocarboxamide synthase activity
  • SAICARs activity
  • 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity
  • 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity
  • SAICAR synthetase activity
  • 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)
  • phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity
  • SAICAR synthase activity
  • phosphoribosylaminoimidazole-succinocarboxamide synthetase activity
Proteins in PDR annotated with:
   This term: 24 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (interactive image map)
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