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Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: deoxyribonuclease I activity
Acc: GO:0004530
Aspect: Molecular Function
Desc: Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
Synonyms:
  • thymonuclease activity
  • DNA depolymerase activity
  • deoxyribonuclease A
  • DNA endonuclease activity
  • alkaline deoxyribonuclease activity
  • alkaline DNase activity
  • DNAase activity
  • endodeoxyribonuclease I
  • Escherichia coli endonuclease I
  • DNase activity
  • pancreatic deoxyribonuclease
  • deoxyribonuclease (pancreatic)
  • dornavac
  • dornava
  • deoxyribonucleic phosphatase activity
  • pancreatic DNase activity
  • thymonuclease, dornase activity
  • DNA nuclease activity
  • DNase I
  • pancreatic dornase
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004530 - deoxyribonuclease I activity (interactive image map)
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