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Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. Catalysis of the hydrolysis of any glycosyl bond. Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine. Catalysis of the hydrolysis of any O-glycosyl bond.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: galactosylceramidase activity
Acc: GO:0004336
Aspect: Molecular Function
Desc: Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
Synonyms:
  • D-galactosyl-N-acylsphingosine galactohydrolase activity
  • galactocerebroside-beta-D-galactosidase activity
  • galactosylcerebrosidase activity
  • galactosylceramidase I
  • cerebroside galactosidase activity
  • cerebroside beta-galactosidase activity
  • galcerase activity
  • lactosylceramidase I
  • beta-galactosylceramidase activity
  • beta-galactocerebrosidase activity
  • galactocerebroside galactosidase activity
  • lactosylceramidase activity
  • galactosylceramide.beta-galactosidase activity
  • galactocerebrosidase activity
  • galactosylceramide beta-galactosidase activity
  • ceramide galactosidase activity
  • galactocerebroside beta-galactosidase activity
  • galactocerebroside.beta-galactosidase activity
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004336 - galactosylceramidase activity (interactive image map)
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Created and Maintained by: Michael Riffle