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Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein. Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)). Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
Acc: GO:0004078
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)).
Synonyms:
  • biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity
  • biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)
  • holocarboxylase-synthetase activity
  • biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity
  • biotin-methylcrotonoyl-CoA-carboxylase ligase activity
  • beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity
  • biotin-methylcrotonoyl-CoA-carboxylase synthetase
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004078 - biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle