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Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: aspartate-ammonia ligase activity
Acc: GO:0004071
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine.
Synonyms:
  • asparagine synthetase activity
  • L-asparagine synthetase activity
  • L-aspartate:ammonia ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004071 - aspartate-ammonia ligase activity (interactive image map)

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