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Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides. Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose. Catalysis of the hydrolysis of any O-glycosyl bond.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
Acc: GO:0003944
Aspect: Molecular Function
Desc: Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.
Synonyms:
  • phosphodiester glycosidase activity
  • 2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity
  • alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity
  • glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity
  • alpha-N-acetylglucosaminyl phosphodiesterase activity
  • lysosomal alpha-N-acetylglucosaminidase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003944 - N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity (interactive image map)
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