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A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response. A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response. A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response. The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: natural killer cell inhibitory signaling pathway
Acc: GO:0002769
Aspect: Biological Process
Desc: A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.
Synonyms:
  • inhibitory KIR signaling pathway
  • Ly49 inhibitory receptor signaling pathway
  • natural killer cell inhibitory signalling pathway
  • killer cell inhibitory receptor signaling pathway
  • NK cell inhibitory signaling pathway
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002769 - natural killer cell inhibitory signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle