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The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages. Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. Any process that stops, prevents or reduces the frequency, rate or extent of monocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. Any process that decreases the rate, frequency or extent of mast cell differentiation, the process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. Any process that stops, prevents or reduces the frequency, rate or extent of granulocyte differentiation. Any process that modulates the frequency, rate or extent of myeloid cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of myeloid leukocyte differentiation
Acc: GO:0002762
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
Synonyms:
  • inhibition of myeloid leukocyte differentiation
  • down-regulation of myeloid leukocyte differentiation
  • downregulation of myeloid leukocyte differentiation
  • down regulation of myeloid leukocyte differentiation
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 31 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002762 - negative regulation of myeloid leukocyte differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle