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Any process of the immune system that occurs as part of an immune response. Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. Any process that modulates the frequency, rate, or extent of granuloma formation. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. Any process that modulates the frequency, rate, or extent of an immune effector process.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of granuloma formation
Acc: GO:0002632
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.
Synonyms:
  • down regulation of granuloma formation
  • inhibition of granuloma formation
  • downregulation of granuloma formation
  • down-regulation of granuloma formation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002632 - negative regulation of granuloma formation (interactive image map)
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