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The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: positive regulation of antigen processing and presentation of peptide antigen via MHC class I
Acc: GO:0002591
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
Synonyms:
  • positive regulation of peptide antigen processing and presentation via MHC class I
  • upregulation of antigen processing and presentation of peptide antigen via MHC class I
  • up-regulation of antigen processing and presentation of peptide antigen via MHC class I
  • stimulation of antigen processing and presentation of peptide antigen via MHC class I
  • up regulation of antigen processing and presentation of peptide antigen via MHC class I
  • activation of antigen processing and presentation of peptide antigen via MHC class I
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002591 - positive regulation of antigen processing and presentation of peptide antigen via MHC class I (interactive image map)

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