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The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. Any process involved in the carrying out of an immune response by a mast cell. The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. The regulated release of histamine by a cell or group of cells. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. The regulated release of histamine by a mast cell or group of mast cells. The regulated release of histamine by a cell or group of cells as part of an inflammatory response. The regulated exocytosis of secretory granules by a leukocyte.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: histamine secretion by mast cell
Acc: GO:0002553
Aspect: Biological Process
Desc: The regulated release of histamine by a mast cell or group of mast cells.
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002553 - histamine secretion by mast cell (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle