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The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation. The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation. The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation. Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation. The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: proteolysis associated with antigen processing and presentation
Acc: GO:0002496
Aspect: Biological Process
Desc: The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002496 - proteolysis associated with antigen processing and presentation (interactive image map)

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Created and Maintained by: Michael Riffle