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The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
Acc: GO:0002485
Aspect: Biological Process
Desc: The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
Synonyms:
  • endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent
  • TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
  • TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002485 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (interactive image map)
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