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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. Any process by which B cells are selected to survive based on signaling through the B cell antigen receptor. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion. Any B cell selection process that occurs in the periphery. Any B cell selection process that occurs in the bone marrow. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: B cell selection
Acc: GO:0002339
Aspect: Biological Process
Desc: The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
Synonyms:
  • B lymphocyte selection
  • B-lymphocyte selection
  • B-cell selection
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002339 - B cell selection (interactive image map)

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