YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The process by which an immature B cell becomes committed to become a B-1 B cell. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby transitional stage B cells acquire the specialized features of mature B cells in the spleen. The process whereby a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: B-1 B cell lineage commitment
Acc: GO:0002336
Aspect: Biological Process
Desc: The process by which an immature B cell becomes committed to become a B-1 B cell.
Synonyms:
  • B-1 B-lymphocyte lineage commitment
  • B-1 B lymphocyte lineage commitment
  • B-1 B-cell lineage commitment
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002336 - B-1 B cell lineage commitment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle