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The process whereby transitional stage B cells acquire the specialized features of mature B cells in the spleen. The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region. The process whereby a nave B cell acquires the specialized features of a mature or memory B cell during an immune response. The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: follicular B cell differentiation
Acc: GO:0002316
Aspect: Biological Process
Desc: The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
Synonyms:
  • follicular B lymphocyte differentiation
  • follicular B-lymphocyte differentiation
  • follicular B-cell differentiation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002316 - follicular B cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle