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Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Any process of the immune system that occurs as part of an immune response. The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. Any process that initiates an immune response. Any process that stops, prevents or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. An immune response mediated through a body fluid. Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of membrane attack complex
Acc: GO:0001905
Aspect: Biological Process
Desc: The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.
Synonyms:
  • membrane attack complex formation
  • MAC assembly
  • activation of terminal complement complex
  • MAC formation
  • activation of MAC
  • membrane attack complex assembly
  • activation of the terminal complement cascade
  • activation of TCC
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001905 - activation of membrane attack complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle