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Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. The process by which the two exons of a pre-tRNA which has had the intron removed are rejoined where the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process. The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. The process by which the two exons of a pre-tRNA which has had the intron removed are rejoined where the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans. The process by which the two exons of a pre-tRNA which has had the intron removed are rejoined where the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species. The process by which the two exons of a pre-tRNA which has had the intron removed are rejoined. The process of joining two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction. The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA exon ligation
Acc: GO:0000968
Aspect: Biological Process
Desc: The process by which the two exons of a pre-tRNA which has had the intron removed are rejoined.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000968 - tRNA exon ligation (interactive image map)
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