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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: N-acetylglucosaminylphosphatidylinositol deacetylase activity
Acc: GO:0000225
Aspect: Molecular Function
Desc: Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
Synonyms:
  • GlcNAc-PI deacetylase activity
  • GlcNAc-PI de-N-acetylase activity
  • acetylglucosaminylphosphatidylinositol deacetylase activity
  • N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
  • 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
  • N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000225 - N-acetylglucosaminylphosphatidylinositol deacetylase activity (interactive image map)
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