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Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase. A ubiquitin-protein ligase activity that increases the rate or extent of the metaphase to anaphase transition of the mitotic cell cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mitotic anaphase-promoting complex activity
Acc: GO:0090302
Aspect: Molecular Function
Desc: A ubiquitin-protein ligase activity that increases the rate or extent of the metaphase to anaphase transition of the mitotic cell cycle.
Synonyms:
  • ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0090302 - mitotic anaphase-promoting complex activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle