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Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. The process by which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA. The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. The process by which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA. Any process by which RNA molecules inactivate expression of target genes. Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: siRNA loading onto RISC involved in chromatin silencing by small RNA
Acc: GO:0070923
Aspect: Biological Process
Desc: The process by which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA.
Synonyms:
  • chromatin silencing by small RNA, siRNA loading onto RISC
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070923 - siRNA loading onto RISC involved in chromatin silencing by small RNA (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle